SPAKOWICZ LAB · THE OHIO STATE UNIVERSITY
Microbiome science
for better cancer outcomes.
We study how microbes shape cancer and cancer therapy—with the goal of making treatment more effective and better tolerated.
Our work connects patient studies, experimental models, and computational analysis to turn discoveries about the microbiome into strategies for better care.
OUR APPROACH
From patients to mechanisms.
From discovery to intervention.
Clinical discovery
Study microbial features associated with treatment response, toxicity, and outcomes in people with cancer.
02Mechanistic discovery
Test how microbes, communities, and metabolites influence tumor biology and the immune response.
03Microbiome intervention
Explore microbial and dietary strategies to improve the effectiveness and tolerability of cancer therapy.
HOW WE WORK
Connected by collaboration.
Built to be shared.
We bring clinicians, microbiologists, and computational scientists together, sharing data and ideas early to shape the questions we ask and the experiments we run.
Reproducible analysis is part of every stage of discovery. We develop transparent methods for complex microbiome and clinical datasets, and share the tools and workflows we build so others can use and extend them.
SCIENCE IS A TEAM EFFORT